General Cell Lines and Cell Cultures
ABclonal Technology NPSR1 Rabbit pAb
This gene encodes a member of the vasopressin/oxytocin subfamily of G protein-coupled receptors. The encoded membrane protein acts as a receptor for neuropeptide S and affects a variety of cellular processes through its signaling. Increased expression of this gene in ciliated cells of the respiratory epithelium and in bronchial smooth muscle cells is associated with asthma. Polymorphisms in this gene have also been associated with asthma susceptibility, panic disorders, inflammatory bowel disease, and rheumatoid arthritis. Alternative splicing results in multiple transcript variants.
Biochain Institute Inc Frozen Tissue Section - Human Diabetic Diseased Tissue: Bone Marrow, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's Frozen Tissue Slides are ideal for rapidly identifying cellular localization of RNA or protein. A single human adult normal tissue with 5-10 um thickness is mounted on a positively charged glass slide. The slides are fixed and dehydrated with acetone for consistent results with in situ hybridization and immunohistochemistry. More organs may be available upon request.
Biochain Institute Inc Frozen Tissue Section Panel - Mouse Whole Brain Segmentation Panel, 5 slides/PK
Whole brain segmentation panels are designed for study whole brain of small animals. The animals' whole brain was procured intact and was sliced into 6 equal coronal regions. Each region is 2 mm thick. The 6 regions were embedded in the same OCT block. The frozen section panel cut from this block can enable scientists or research investigators do biochemical analysis, such as the determination of neurotransmitter and metabolite concentrations for reproducible brain regions (i.e. discrete terminal fields or nuclei).
ATCC Bacillus cereus; Strain NRRL B-569; genomic DNA
Genomic DNA isolated from Bacillus cereus strain NRRL B-569. This bacterial strain is also available as ATCC Catalog No. 10876™.
Eurofins Discoverx ChemiScreen FP Prostanoid Receptor Stable Cell Line, 2 vials. (HTS093C)
The ChemiScreen FP Prostanoid Receptor Stable Cell Line is an engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. prostaglandin F2a) based activation of PTGFR GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses PTGFR alongside endogenous high levels of the promiscuous G protein, Gα15, coupling the receptor to the calcium signaling pathway. Upon activation of PTGFR, the resulting calcium activity can be fluorescently assayed. This stable modified cell line is provided as two vials of cryopreserved cells. For detailed product information, visit www.discoverx.com/targets/gpcr-target-biology.
ATCC Quantitative Genomic; RNA from Sendai virus; Strain: Cantell
ATCC Genuine Nucleics can be used for assay development, verification, validation, monitoring of day-to-day test variation, and lot-to-lot performance of molecular-based assays. The quantitative format allows for the generation of a standard curve for quantitative PCR (qPCR) to determine viral load.
Eurofins Discoverx Ready-to-Assay C3a Anaphylotoxin Receptor Frozen Cells, 2 Vials of Cells. (HTS016RTA)
The Ready-to-Assay C3a Anaphylotoxin Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. C3a) based activation of C3AR1 GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses C3AR1 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of C3AR1, the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the stably modified clonal cell line in a convenient thaw-and-use format. For detailed product information, User manual and datasheet, visit www.discoverx.com/products-applications/frozen-cells.
Eurofins Discoverx ChemiScreen M3 Muscarinic Acetylcholine Receptor Membrane Preparation, 1 vial. (HTS116M)
The ChemiScreen M3 Muscarinic Acetylcholine Receptor Membrane Preparation is derived from proprietary stable recombinant cells to ensure high levels of CHRM3 surface expression. ChemiScreen membrane preps can be used to screen for ligand binding affinities using a competitive radio-labeled ligand approach. Increased binding affinities will lead to higher radioactive signal. Membrane preps contain 1 mL of 1 mg/mL frozen membranes derived from a stably modified clonal cell line which was chosen for optimal receptor expression. For detailed product information, visit www.discoverx.com/membranepreps.
Amsbio LLC Human HCT116 / Luciferase & RFP Stable Cells
Human HCT116 / Luciferase & RFP Stable Cells
Biochain Institute Inc Paraffin Tissue Section - Human Diabetic Diseased Tissue: Small Intestine: Jejunum, 5 slides/PK
BioChain's tissue products are based on the sample repository network established following the IRB-approved ethical standard and procedures. BioChain's formalin fixed paraffin embedded (FFPE) tissue section line encompasses a large selection of tissue sections which are suitable for immunohistochemistry and in situ hybridization assays. The tissue sections are approximately 5 um thick. Each slide contains tissue from single human diseased sample. Documentation of tissues' clinical histories may be available upon request. For those customers who want to perform FFPE DNA and RNA isolation, BioChain can provide tissue section slices in tubes instead of mounting them on glass slides.
Amsbio LLC Lyophilized exosomes from Plasma of Healthy donors
Lyophilized exosomes from Plasma of Healthy donors